喂养方式对小于胎龄儿早期发展的影响
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1.Dujiangyan Municipal People'2.'3.s Hospital

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四川省营养学会妇幼营养研究基金(SCNC-MCNR2025-01)


Effects of feeding patterns on early development in small for gestational age Infants
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    摘要:

    目的 探讨不同喂养方式对小于胎龄儿(SGA)早期发育的影响,为SGA儿童喂养策略提供临床依据。方法 选取2022年4月—2025年4月都江堰市人民医院产科出生,并在儿保门诊系统管理的SGA儿童,根据喂养方式分为纯母乳喂养组、混合喂养组、人工喂养组,选取同期出生的适于胎龄儿(AGA)作为对照。比较各组体格发育、神经心理发育情况。结果 1.SGA纯母乳喂养组3月龄时体重Z值、身高追赶生长发生率,6月龄体重追赶生长发生率,均显著低于人工喂养组,6月龄后体重及身高差异逐渐减小且无统计学差异。2.纯母乳喂养组肥胖发生率显著低于人工喂养组。3.头围Z值比较无统计学差异。4.SGA人工喂养组语言、适应能力、社交行为发育商显著低于AGA组及纯母乳喂养组;纯母乳喂养组各维度发育商与AGA组比较无统计学差异。结论 1.SGA儿童纯母乳喂养在0-12月龄显示出更匀速、更持久的追赶生长,其生长速率更稳定;2.不同喂养方式未影响SGA儿童12月龄体格追赶生长结局,但纯母乳喂养肥胖发生风险更低;3.SGA儿童大部分在生后第一年实现追赶生长,以6月龄以下更为显著;4.纯母乳喂养的SGA儿童有更高的神经心理发育水平,与AGA儿童相似。

    Abstract:

    Objective To investigate the effects of different feeding methods on the early development of small-for-gestational-age (SGA) infants, and to provide clinical evidence for feeding strategies in SGA children. Methods SGA children born at the Department of Obstetrics, People''s Hospital of Dujiangyan City from April 2022 to April 2025 and systematically managed in the pediatric outpatient clinic were selected. They were divided into exclusive breastfeeding group, mixed feeding group, and formula feeding group according to feeding methods. Appropriate-for-gestational-age (AGA) infants born during the same period were selected as controls. Physical growth and neuropsychological development were compared among groups. Results 1. At 3 months of age, the weight Z-score and incidence of catch-up growth in height, and at 6 months of age, the incidence of catch-up growth in weight were significantly lower in the exclusive breastfeeding group than in the formula feeding group; after 6 months, the differences gradually decreased and showed no statistical significance. 2. The incidence of obesity was significantly lower in the exclusive breastfeeding group than in the formula feeding group. 3. No statistically significant difference was found in head circumference Z-scores. 4. The developmental quotients for language, adaptive ability, and social behavior in the formula-fed SGA group were significantly lower than those in the AGA group and the exclusive breastfeeding group; no statistically significant differences were observed between the exclusive breastfeeding group and the AGA group across all developmental dimensions. Conclusion 1. Exclusive breastfeeding in SGA children aged 0–12 months demonstrates more uniform and sustained catch-up growth with a more stable growth rate. 2. Different feeding methods do not affect the physical catch-up growth outcome of SGA children at 12 months of age, but exclusive breastfeeding is associated with a lower risk of obesity. 3. Most SGA children achieve catch-up growth within the first year of life, especially before 6 months of age. 4. Exclusively breastfed SGA children exhibit higher levels of neuropsychological development, comparable to those of AGA children.

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  • 收稿日期:2026-06-30
  • 最后修改日期:2026-09-02
  • 录用日期:2026-11-04
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