Abstract:Objective:Using resting state functional magnetic resonance imaging(rs-fMRI)analysis tinnitus cranii and tinnitus local brain function changes and functional connection between brain areas of difference,provide new way for the diagnosis and classifi-cation of tinnitus.Methods:This study included 20 patients with tinnitus cranii,20 patients with tinnitus,and collected their clinical da-ta and RS-fMRI data.The SPM 12 software of Matlab 2021b platform and DPABI 6.3 toolkit were used to analyze the data.The differ-ences of ReHo and FC among the groups were calculated.Results:The ReHo value of the right central sulci in the tinnitus cranii group was higher than that in the tinnitus group(P<0.005).The functional connections between the left anterior cingulate gyrus and the right inferior temporal gyrus,the right inferior frontal gyrus of the insular cap and the right central sulci gyrus in the tinnitus cranii group were lower than those in the tinnitus group,and the functional connections between the left anterior cuneus and the right superior mar-ginal gyrus in the tinnitus cranii group were lower than those in the tinnitus group.Conclusion:There are differences in neural activity and functional connections between brain regions between tinnitus and tinnitus cranii patients,which may be related to the different spa-tial perception of auditory hallucinations.