Objective:To evaluate the therapeutic effect of dual needle bipolar pulsed radiofrequency therapy under ultrasound combined with CT dual guidance for elderly patients with herpes zoster neuralgia.Methods:60 elderly patients with thoracic and lumbar herpes zoster neuralgia were selected and divided into observation group and control group according to different treatment methods,with 30 cases in each group.The observation group was treated with double-needle bipolar pulsed radiofrequency operation,the control group was treated with single-needle unipolar pulsed radiofrequency operation.Pain was evaluated by pain VAS score before operation,the 3 day after operation,the 1 month after operation and the 3 month after operation.GQOL-74 was used to evaluate the quality of life before operation and 3 month after operation.The dosage of gabapentin before operation,the 3 day after operation,the 1 month after operation and the 3 month after operation were counted,and the operation time,the incidence of PHN and the incidence of adverse reactions were also counted.Results:At different time points after operation,the VAS scores and the dosage of gabapentin of the two groups were lower than those before operation(P＜0.05),and the observation group was lower than the control group(P＜0.05).The scores of GQOL-74 in the two groups were higher than those before operation(P＜0.05),and the observation group was higher than the control group(P＜0.05).The incidence of PHN in the observation group was lower than that in the control group(P＜0.05).There was no signifi-cant difference in the incidence of adverse reactions(P＞0.05).Conclusion:The dual needle bipolar pulsed radiofrequency therapy under ultrasound and CT dual guidance has a significant therapeutic effect on elderly patients with herpes zoster neuralgia,with no ad-verse reactions,and is worthy of promotion.