Objective:To explore the prevalence of hypertension and prehypertension and its influencing factors in young and middle-aged healthy people in Nanchong Central Hospital.Methods:46,740 middle-aged and young adults(18～44 years old as young adults,45～59 years old as middle-aged adults)were selected as the research objects.They were divided into hypertension group(n=11,751),prehypertension group(n=17,522),and normal blood pressure group(n=17,467)according to blood pressure values.The differences in age,gender,height,weight,blood pressure,blood glucose,lipid and uric acid among groups were compared.Multivariate Logistic regression model was used to analyze the influencing factors of hypertension and prehypertension.Results:The total population of the study was 46,740 young and middle-aged patients,including 11,751 patients with hypertension and 17,522 patients with prehy-pertension.The prevalence rate of hypertension and prehypertension was 62.6％.The prevalence of hypertension was higher in males than in females(71.3％ vs.28.7％,P＜0.05),and higher in middle-aged group than in young group(74.7％vs.25.3％,P＜0.05).The prevalence of prehypertension was higher in men than in women(62.1％ vs.37.9％,P＜0.05)and higher in middle-aged group than in young group(55.2％ vs.44.8％,P＜0.05).In addition,the mean values of body mass index,total cholesterol,low den-sity lipoprotein cholesterol,triglyceride,fasting blood glucose,serum creatinine and uric acid in hypertension group were higher than those in prehypertension group,and both groups were higher than those in normal blood pressure group(P＜0.05).The high density lipoprotein cholesterol in the hypertension group was lower than the prehypertension group and the normal blood pressure group,and the prehypertension group was lower than the normal blood pressure group(P＜0.05).The detection rate of overweight and obesity in hy-pertension group with abnormal blood glucose,lipid and uric acid metabolism was higher than that in prehypertension group,and both groups were higher than that in normal blood pressure group(P＜0.05).Logistic analysis showed that male,middle age,overweight/o-besity,hyperglycemia,hypercholesterolemia,hypertriglyceridemia,mixed hyperlipidemia and hyperuricemia were independent risk fac-tors for hypertension and prehypertension(P＜0.05).Conclusion:The prevalence rates of hypertension and prehypertension were higher in young and middle-aged healthy people in Nanchong Central Hospital.Male,middle-aged,overweight/obesity,hyperglycemia,hypercholesterolemia,hypertriglyceridemia,mixed hyperlipidemia and hyperuricemia were closely related to the incidence of hyperten-sion and prehypertension in young and middle-aged healthy people.Male,middle-aged,overweight/obesity are the strongest risk factors.Early intervention should be helpful for the prevention and control of hypertension in young and middle-aged people.