恶性贫血合并免疫性血小板减少症1例
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R556;R558.2

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四川省南充市市校科技战略合作项目(225XZRKX007); 川北医学院临床医学院·附属医院科研发展计划项目(2024GC009);


A case of pernicious anemia complicated with immune thrombocytopenia
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    摘要:

    <正>1病例资料患者,女,57岁,因“腹痛、乏力1月,发现血小板减少20 d”于2022年2月18日入川北医学院附属医院血液内科。患者1个月前无明确诱因出现上腹间断疼痛,伴乏力,偶有头晕。20 d前患者外院行血常规示血小板44×10~9/L,血红蛋白120 g/L,总胆红素42.2μmol/L,间接胆红素30.9μmol/L,以急性胃肠炎治疗后腹痛减轻,但仍有间断腹痛,复查血常规示血小板29×10~9/L,血红蛋白115 g/L,院外予以升血小板胶囊疗效不佳故收治入院。患者无素食及偏食习惯,长期便秘,体质量无明显变化,胃炎病史10+年,平素有反酸、打嗝、烧心、腹胀,近1年进食时感舌头疼痛、焦虑、失眠,曾有自杀倾向,偶有全身多处关节疼痛及指端麻木。

    Abstract:

    < positive >1 case data the patient, a 57 year old female, was admitted to the Department of Hematology of the Affiliated Hospital of North Sichuan Medical College on February 18, 2022 because of "abdominal pain and fatigue for 1 month and thrombocytopenia for 20 days". The patient had intermittent pain in the upper abdomen without clear inducement 1 month ago, accompanied by fatigue and occasional dizziness. 20 days ago, the blood routine of the patient outside the hospital showed that the platelet was 44 × 10-9 / L, hemoglobin was 120 g / L, total bilirubin was 42.2 μ mol/l, indirect bilirubin was 30.9 μ mol/l, and the abdominal pain was alleviated after the treatment of acute gastroenteritis, but there was still intermittent abdominal pain. The blood routine reexamination showed that the platelet was 29 × 10-9 / L, hemoglobin was 115 g / L. the effect of platelet raising capsule outside the hospital was poor, so he was admitted to the hospital. The patient has no vegetarian and partial eating habits, long-term constipation, no significant change in body mass, and has a history of gastritis for 10+ years. She usually has acid regurgitation, hiccups, heartburn, and abdominal distension. She has felt tongue pain, anxiety, and insomnia when eating for nearly 1 year, has suicidal tendencies, and occasionally has multiple joint pain and finger numbness.

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何虹秀;林晓静;.恶性贫血合并免疫性血小板减少症1例[J].川北医学院学报,2025,40(7):940-942.

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  • 在线发布日期: 2025-08-10
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