Objective:To explore the early diagnostic value of(1-3)β-D glucan test(G test)and galactomannantest(GM test)in serum and bronchoalveolar lavage fluid(BALF)for patients with invasive pulmonary fungal infection(IPFI).Methods:A total of 53 patients with IPFI and 53 patients with pulmonary bacterial infectionin the hospital were enrolled as IPFI group and control group,respectively.All patients underwent G test and GM test in serum and bronchoalveolar lavage fluid,and the detection results in the two groups were compared.The diagnostic value of G test and GM test in serum and alveolar lavage fluid was analyzed.Results:The results of serum G test,GM test,alveolar G test and GM test were different between the two groups(P<0.05).Taking results of histopatholog-ical examination as the golden standard,sensitivity,specificity,accuracy,positive predictive value and negative predictive value of serum G test,serum GM test,bronchoalveolar lavage fluid G test and bronchoalveolar lavage fluid GM test in the diagnosis of IPFI were(69.81%,100.00%,84.91%,100.00%,76.81%),(41.51%,100.00%,70.75%,100.00%,63.10%),(100.00%,73.58%,86.79%,79.10%,100.00%)and(77.36%,64.15%,70.75%,68.33%,73.91%),respectively.ROC curves analysis showed that area under the curve(AUC)values of serum G test,serum GM test,bronchoalveolar lavage fluid G test and bronchoalveolar lavage fluid GM test in the diagnosis of pulmonary fungal infection were 0.804,0.862,0.978 and 0.987,all of which had certain discriminatory val-ue for IPFI.Conclusion:G test and GM test in serum and bronchoalveolar lavage fluid all have certain diagnostic value for IPFI.Ac-cording to different thresholds,they have their own advantages and disadvantages in terms of sensitivity and specificity.Clinically,com-prehensive assessment should be conducted based on actual situation and multiple detection results.