Objective:To explore the effect of cluster nursing program based on the concept of enhanced recovery after sur-gery(ERAS)on postoperative delirium(POD)in elderly patients with hip fracture.Methods:168 elderly patients with hip frac-ture were divided into control group(n=84)and observation group(n=84)according to different nursing methods.The con-trol group was given routine perioperative nursing,and the observation group was given cluster nursing based on ERAS con-cept.The incidence of postoperative POD(incidence,duration),the incidence of postoperative hypoxemia,the visual analogue scale(VAS)of pain on the first day after operation,the total sleep time on the first day after operation,the incidence of POD-related adverse events and postoperative recovery(Orientation recovery time after anesthesia,hospitalization time)were com-pared between the two groups.Results:Compared with the control group,the incidence of POD in the observation group(26.19％vs.10.71％)was lower,and the duration of POD[(3.70±0.95)d vs.(2.37±0.72)d]was shorter(P＜0.05).The incidence of hypoxemia in the observation group was lower than that in the control group(15.48％vs.8.33％,P＞0.05).Compared with the control group,the VAS score of the observation group on the first day after operation was lower[(4.26±1.04)points vs.(2.61±0.75)points,P＜0.001],and the total sleep time on the first day after operation was longer[(3.71±0.72)h vs.(5.30±0.64)h,P＜0.001].The total incidence of POD-related adverse events in the observation group was lower than that in the control group(11.90％vs.3.57％,P＜0.05).Compared with the control group,the Orientation recov-ery time after anesthesia[(4.11±0.97)h vs.(2.55±0.68)h]and hospitalization time[(7.64±1.53)d vs.(6.76±1.28)d]in the observation group were shorter(P＜0.05).Conclusion:The cluster nursing program based on the concept of ERAS can effectively reduce the incidence and duration of POD in elderly patients with hip fracture,reduce the occurrence of POD-re-lated adverse events,and accelerate postoperative recovery.