高压氧联合支架植入术治疗脑梗死合并颅外段血管狭窄的疗效分析
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江苏省科技计划项目(BK20231160);


Effect of hyperbaric oxygen combined with carotid artery stenting in the treatment of cerebral infarction with extracranial vascular stenosis
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    摘要:

    目的:探讨高压氧联合支架植入术(CAS)治疗脑梗死合并颅外段血管狭窄的疗效及其对患者肢体功能康复的影响。方法:纳入82例脑梗死合并颅外段血管狭窄患者为研究对象,根据治疗方法不同分为联合组与对照组,每组各41例。对照组接受CAS治疗;联合组在对照组基础上接受高压氧治疗,比较两组患者治疗后的临床疗效及肌力情况,并比较治疗前后两组患者的肢体功能和认知功能评分。结果:联合组的总有效率为97.56%,高于对照组的80.49%(P<0.05);治疗后,联合组的肌力情况优于对照组(P<0.05);治疗后,两组FMA各维度评分及总分高于治疗前,且联合组高于对照组(P<0.05);治疗后,两组MMSE和MoCA评分高于治疗前(P<0.05),且联合组高于对照组(P<0.05)。结论:高压氧联合CAS治疗脑梗死合并颅外段血管狭窄的疗效确切,可有效改善患者的认知功能,同时提高患者肌力,对肢体功能康复有积极作用。

    Abstract:

    Objective:To explore the efficacy of hyperbaric oxygen combined with stent implantation(CAS)in the treat-ment of cerebral infarction complicated with extracranial segment vascular stenosis,as well as its influence on the rehabilitation of limb function in patients.Methods:A total of 82 patients with cerebral infarction complicated with extracranial vascular ste-nosis were included in this study.They were divided into the combined group and the control group according to different treat-ment methods,with 41 cases in each group.The control group received CAS treatment,and the combined group received hyper-baric oxygen therapy on the basis of the control group.The clinical efficacy and muscle strength of the two groups of patients after treatment were compared,and the limb function and cognitive function scores of the two groups of patients before and af-ter treatment were also compared.Results:The total effective rate of the combined group was higher than that of the control group(97.56%vs.80.49%,P<0.05).After the treatment,the muscle strength classification of the combined group was bet-ter than that of the control group(P<0.05).The total scores of the upper limbs,lower limbs and FMA in the combined group and the control group after treatment were all higher than those before treatment(P<0.05),and the combined group was higher than the control group(P<0.05).The MMSE and MoCA scores of the combined group and the control group after treatment were both higher than those before treatment(P<0.05),and the combined group was higher than the control group(P<0.05).Conclusion:Hyperbaric oxygen combined with CAS has a definite therapeutic effect on cerebral infarction compli-cated with extracranial segment vascular stenosis.It can effectively improve the cognitive function of patients,and is also condu-cive to enhancing the muscle strength of patients,which has a positive effect on the rehabilitation of limb function of patients.

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王临风;周一凡;谢满意;聂耳;李中林;.高压氧联合支架植入术治疗脑梗死合并颅外段血管狭窄的疗效分析[J].川北医学院学报,2025,40(10):1249-1252.

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  • 在线发布日期: 2025-11-03
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