Abstract:Objective:To investigate the effects of combining visual function training with different optical correction mo-dalities on ocular accommodative function and refractive-related parameters in myopic children and adolescents,aiming to evalu-ate their combined efficacy in myopia control and prevention.Methods:This study enrolled 120 patients(240 eyes)meeting in-clusion criteria,they were divided into 6 groups according to different correction methods:single-vision lenses(SVL),defocus incorporated multiple segments(DIMS),orthokeratology(OK),and their respective combinations with vision training(SCVT,DCVT,OCVT),with 20 patients(40 eyes)in each group.Optical correction groups wore lenses only,while combined groups received additional accommodative training.Changes in axial length(AL),anterior chamber depth(ACD),mean keratometry(Km),accommodative amplitude(AMP),accommodative facility(AF),positive relative accommodation(PRA),and negative relative accommodation(NRA)were assessed before intervention and 3 and 6 months after intervention treatment.Results:Af-ter the intervention,in optical correction groups,SVL showed no significant changes,DIMS improved AF(P<0.05),OK im-proved AMP,AF,PRA,and reduced ACD,Km(P<0.05).In combined groups,SCVT improved AMP,AF(P<0.05),DCVT improved AMP,AF,PRA,NRA(P<0.05),OCVT improved AMP,AF,PRA,NRA,and reduced ACD,Km(P<0.05).Com-bined groups showed better AL control and AMP,AF,PRA improvements than in optical correction groups(P<0.05).A-mong combined groups,DCVT and OCVT outperformed SCVT in AMP,AF,PRA improvements(P<0.05),OCVT sur-passed DCVT in AMP improvements(P<0.05).After 6 months of intervention,AL growth was OCVT