外周血PLR联合RTS评分对急诊创伤患者28 d预后的预测价值
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R641

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广东省医学科研基金项目(B2022169);


Predictive value of peripheral blood PLR combined with RTS score for 28-day prognosis of emergency trauma patients
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    摘要:

    目的:探讨外周血血小板与淋巴细胞比值(PLR)联合修正创伤评分(RTS)对急诊创伤患者28 d预后的预测价值。方法:回顾性分析108例急诊创伤患者临床资料。按28 d预后不同,将患者分为存活组(n=91)与死亡组(n=17)。比较两组患者一般资料和白细胞计数、PLR等实验室指标差异。采用Logistic回归分析确定患者预后的危险因素;并用受试者工作特征(ROC)曲线评价相关指标对患者28 d预后的预测价值。结果:与存活组相比,死亡组行急诊机械通气的比例增高(P<0.05),RTS评分下降(P<0.05),损伤严重程度评分(ISS)增高(P<0.05)。与存活组相比,死亡组血小板计数和PLR均下降(P<0.05);两组其他常规实验室指标比较,差异均无统计学意义(P>0.05)。Logistic回归分析显示,急诊机械通气(OR=4.591)、RTS评分(OR=0.708)和PLR(OR=0.776)均为患者28 d预后的独立影响因素(P<0.05)。ROC曲线分析显示,PLR、RTS评分均对急诊创伤患者28 d死亡有一定预测能力,曲线下面积(AUC)分别为0.764、0.736;二者联合的AUC为0.822,高于单一指标(P<0.05)。结论:外周血PLR、RTS评分均与急诊创伤患者28 d预后密切相关,二者联合应用能够更好地预测患者预后。

    Abstract:

    Objective:To investigate the predictive value of peripheral blood platelet-to-lymphocyte ratio(PLR)combined with modified trauma score(RTS)for 28-day prognosis in emergency trauma patients.Methods:The clinical data of 108 pa-tients with emergency trauma were retrospectively analyzed.According to the 28-day prognosis,the patients were divided into survival group(n=91)and death group(n=17).The general data and laboratory indexes such as white blood cell count and PLR were compared between the two groups.Logistic regression analysis was used to determine the risk factors of prognosis.The receiver operating characteristic(ROC)curve was used to evaluate the predictive value of related indicators for the 28-day prognosis of patients.Results:Compared with the survival group,the proportion of emergency mechanical ventilation in the death group was increased(P<0.05),the RTS score was decreased(P<0.05),and the injury severity score(ISS)was in-creased(P<0.05).Compared with the survival group,the platelet count and PLR in the death group decreased(P<0.05).There was no significant difference in other routine laboratory indexes between the two groups(P>0.05).Logistic regression analysis showed that emergency mechanical ventilation(OR=4.591),RTS score(OR=0.708)and PLR(OR=0.776)were independent factors affecting the 28-day prognosis of patients(P<0.05).ROC curve analysis showed that both PLR and RTS scores had certain predictive ability for 28-day death in emergency trauma patients,with AUC of 0.764 and 0.736,respectively.The AUC of the combination of the two was 0.822,which was higher than that of the single index(P<0.05).Conclusion:Pe-ripheral blood PLR and RTS scores are closely related to the 28-day prognosis of emergency trauma patients,and the combina-tion of the two can better predict the prognosis of patients.

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李健宇;黄文汉;冯文浩;钟奇智;刘宁贵;蔡峰;.外周血PLR联合RTS评分对急诊创伤患者28 d预后的预测价值[J].川北医学院学报,2025,40(11):1422-1425.

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  • 在线发布日期: 2025-12-22
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