Objective: to construct the evaluation index system of perioperative nursing quality for patients with Hirschsprung's disease, so as to optimize nursing management, meet patients' personalized needs, ensure continuous and efficient nursing services, and promote patients' rehabilitation. Methods: Based on the "structure process result" model, this study constructed the evaluation index system of perioperative nursing quality for patients with Hirschsprung's disease by integrating literature analysis, Delphi expert consultation and analytic hierarchy process, and completed the determination of the weight of each index. Results: the recovery rate of the two questionnaires was 100%, the authority coefficient was 0.908 and 0.917, and the variation coefficient was 0.051 ～ 0.215 and 0.051 ～ 0.229, respectively; The Kendall concordance coefficients were 0.299 and 0.332 (p<0.05), and the consistency coefficients of indicators at all levels were 0.033, 0.034, 0.039, all <0.100. The construction system includes 3 primary indicators, 10 secondary indicators and 55 tertiary indicators. Conclusion: the constructed evaluation index system of perioperative nursing quality for patients with Hirschsprung's disease is scientific and practical, and can objectively evaluate the perioperative nursing quality of patients with Hirschsprung's disease.