逼尿肌功能异常对超声引导下经尿道激光前列腺切除术治疗良性前列腺增生疗效的影响
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R699.8

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浙江省中医药科技计划项目(2025ZL054);


Effect of preoperative detrusor pressure at maximum flow rate on postoperative outcomes after transurethral ultrasound-guided laser-induced prostatectomy for benign prostatic hyperplasia
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    摘要:

    目的:探讨逼尿肌功能异常对经尿道超声引导激光诱导前列腺切除术(TULIP)治疗良性前列腺增生(BPH)疗效的影响。方法:选取124例接受TULIP治疗的BPH患者为研究对象,按术前最大尿流率时逼尿肌压力(PdetQmax)不同分为A组(PdetQmax≤20 cmH2O,n=36)、B组(2040 cmH2O,n=36)。比较三组患者一般资料、围术期指标、术后6个月临床疗效、术前及术后3个月和6个月功能评分、术后3个月排尿功能指标及术后并发症发生情况。结果:三组患者PdetQmax及BCI比较,差异有统计学意义(P<0.05)。与A组相比,B、C组患者术后导尿管留置时间、总住院时间及首次自主排尿时间均较短(P<0.05)。术后6个月,三组患者国际前列腺症状评分(IPSS)改善值及改善率比较,差异有统计学意义(P<0.05),且B、C组患者QoL改善幅度较A组更大(P<0.05)。术后3个月,三组患者PV均下降(P<0.05),Qmax均升高(P<0.05),但A组患者术后PVR仍相对较高(P<0.05)。A组患者术后急性尿潴留发生率高于B组和C组(P<0.05)。结论:TULIP可改善BPH患者症状和排尿功能,但低PdetQmax患者术后客观排尿恢复相对不足,急性尿潴留发生风险较高,术前PdetQmax可作为疗效预期和围术期管理的参考指标。

    Abstract:

    Objective: To investigate the effect of preoperative detrusor pressure at maximum urinary flow rate (PdetQmax) on postoperative outcomes after transurethral ultrasound-guided laser-induced prostatectomy (TULIP) for benign prostatic hyperplasia (BPH). Methods: A total of 124 patients with BPH who underwent TULIP were retrospectively included. According to preoperative PdetQmax, patients were divided into group A (PdetQmax ≤ 20 cmH2O, n = 36), group B (20 < PdetQmax ≤ 40 cmH2O, n = 52), and group C (PdetQmax > 40 cmH2O, n = 36). The general information, perioperative indicators, postoperative clinical efficacy at 6 months, preoperative and postoperative functional scores at 3 and 6 months, postoperative urinary function indicators at 3 months, and incidence of postoperative complications were compared among the three groups. Results: There was a statistically significant difference in PdetQmax and BCI among the three groups (P < 0.05). Compared with group A, groups B and C had shorter postoperative catheterization duration, hospital stay, and time to spontaneous voiding (P < 0.05). Six months after surgery, there was a statistically significant difference in the improvement values and rates of International Prostate Symptom Score (IPSS) among the three groups of patients (P < 0.05), and the improvement in QoL was greater in groups B and C than in group A (P < 0.05). Three months after surgery, PV decreased and Qmax increased in all three groups (P < 0.05), but PVR remained relatively high in group A patients after surgery (P < 0.05). The incidence of postoperative acute urinary retention in group A was higher than that in groups B and C (P < 0.05). Conclusion: TULIP can improve symptoms and voiding function in patients with BPH. However, patients with low PdetQmax show relatively insufficient recovery of objective urinary function and a higher risk of acute urinary retention. Preoperative PdetQmax may serve as a useful reference for outcome expectation and perioperative management.

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曹建舟;王文志;孙艳丽;.逼尿肌功能异常对超声引导下经尿道激光前列腺切除术治疗良性前列腺增生疗效的影响[J].川北医学院学报,2026,41(10):1235-1239.

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  • 在线发布日期: 2026-10-26
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