Bhattarai G, An YH, Shrestha SK, et al. Therapeutic potency and the related mechanism of deinoxanthin in experimental animal and cell models of periodontitis[J]. Sci Rep, 2026, 16(1):5735. Qiu Y, Zhao Y, Jia L, et al. Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ[J]. Anim Cells Syst, 2025, 29(1):19-29.Yang DW, Cui XB, Dong R, et al. Timosaponin B- II Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via PI3K/AKT/GSK3β Signaling Pathway[J]. Stem Cell Rev Rep, 2025, 21(8):2675-2692.Shen Z, Kuang S, Zhang Y, et al. Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism[J]. Bioact Mater, 2020 , 5(4):1113-1126.Muro P, Jing C, Qiao Y, et al. Advances of exosome regulating?FXR to repair inflammatory bowel disease (Review)[J]. Int J Mol Med, 2025, 56(3):135.Robinson KS, Teo DET, Tan KS, et al. Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia[J]. Science, 2020, 370(6521):eaay2002.Zhang Y, Zhao H, Fu X, et al. The role of hydrogen sulfide regulation of pyroptosis in different pathological processes[J]. Eur J Med Chem, 2024, 268:116254.Zhang L, Wang Q, Su H, Cheng J. Exosomes from adipose derived mesenchymal stem cells alleviate diabetic osteoporosis in rats through suppressing NLRP3 inflammasome activation in osteoclasts[J]. J Biosci Bioeng, 2021, 131(6):671-678.Wang L, Liu T, Zhang W, et al. BMAL1 downregulation drives PANoptosis and the osteogenic differentiation impairment of PDLSCs by ERK/AP-1 signaling pathway[J]. J Periodontol, 2025, 96(8):906-919.Yu H, Wang P, Lu H, et al. Effects of G-CSF on hPDLSC proliferation and osteogenic differentiation in the LPS-induced inflammatory microenvironment[J]. BMC Oral Health,? 2023, 26;23(1):422.Zhao L, Tang S, Chen F, et al. Regulation of macrophage polarization by targeted metabolic reprogramming for the treatment of lupus nephritis[J]. Mol Med, 2024, 30(1):96.Daneshvar A, Nemati P, Azadi A, et al. M2 macrophage-derived exosomes for bone regeneration: A systematic review[J]. Arch Oral Biol, 2024, 166:106034.Zhou YK, Han CS, Zhu ZL, et al. M2 exosomes modified by hydrogen sulfide promoted bone regeneration by moesin mediated endocytosis[J]. Bioact Mater, 2023, 31:192-205.Liao XM, Guan Z, Yang ZJ, et al. Comprehensive analysis of M2 macrophage-derived exosomes facilitating osteogenic differentiation of human periodontal ligament stem cells[J]. BMC Oral Health, 2022, 22(1):647.Zhao Y, Huang Y, Liu H, et al. Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes[J]. Stem Cells Int, 2022, 2022:4185972.Gao J, Wu Z. M2 macrophage-derived exosomes enable osteogenic differentiation and inhibit inflammation in human periodontal ligament stem cells through promotion of CXCL12 expression[J]. BMC Oral Health, 2024, 24(1):1070.方俊, 魏伟, 薛亚婷, 等. M2型巨噬细胞衍生外泌体促进小胶质细胞M2型极化[J]. 中国组织工程研究, 2025, 29(25):5320-5327.孙逸梅, 毛诗慧, 李琳, 等. 骨髓间充质干细胞源性外泌体促进小胶质细胞/巨噬细胞M2极化抑制急性期脑缺血大鼠炎症反应[J]. 中国药科大学学报, 2023, 54(05):599-606.Hou C, Zhang Y, Lv Z, et al. Macrophage exosomes modified by miR-365-2-5p promoted osteoblast osteogenic differentiation by targeting OLFML1[J]. Regen Biomater, 2024, 11:rbae018.刘文涛, 冯兴超, 杨毅, 等. M2型巨噬细胞外泌体诱导骨髓间充质干细胞的成骨分化[J]. 中国组织工程研究, 2023, 27(06):840-845.彭巍, 江榕, 李勇, 等. 人诱导多能间充质干细胞来源外泌体对肺泡巨噬细胞焦亡的抑制作用[J]. 中华危重病急救医学, 2021, 33(1):00728.Cheng Y, Zhao P, Zhang N, et al. M2 macrophage-derived extracellular vesicle/polydopamine hydrogel attenuates diabetic periodontitis-induced bone loss via the NEK7/NLRP3/IL-1β pathway[J]. Sci Rep, 2025, 16(1):4080.