Objective:To explore the effect of auricular point sticking combined with foot bath in promoting the postoperative re-covery of patients with adenomyopathy and the mechanism of analgesia and anti-anxiety.Methods:A total of 107 patients with adenomy-opathy who underwent high intensity focused ultrasound(HIFU)were divided into observation group(n=54)and control group(n=53)according to different intervention methods.Patients in the control group were given foot bath intervention after surgery.Observation group was given auricular point sticking intervention on the basis of control group after operation,and both groups were continuously in-tervened for 5 days.The VAS score,TCM syndrome score,mental state[Hospital Anxiety and Depression Scale(HADS)],number of sleep and wake times,serum neurotransmitters[β-endorphin(β-EP),5-hydroxytryptophan(5-HT)]and inflammatory factors[Inter-leukin-6(IL-6),soluble vascular cell adhesion molecule-1(sVCAM-1)],adverse reactions,and recurrence rate within 1 year were compared between the two groups.Results:At 1,3 and 5 d after surgery,the VAS scores in both groups decreased gradually,and the ob-servation group was lower than the control group(P＜0.05).After 5 days of treatment,TCM syndrome score and anxiety HADS(A)score were lower in both groups than those of 1 day after surgery(P＜0.05).The observation group was lower than the control group(P＜0.05).The number of sleep and wake times within 5 days after surgery in the observation group was lower than that in the control group(P＜0.005).After 5 days of treatment,the serum levels of β-EP and 5-HT in the two groups were higher than 1 day after surgery(P＜0.05),and the observation group was higher than the control group(P＜0.05).The levels of IL-6 and sVCAM-1 were lower than 1 day after surgery(P＜0.05),and the observation group was lower than the control group(P＜0.05).After 1 year of follow-up,there was no statistically significant difference in the recurrence rate between the two groups(P＞0.05).Conclusion:Auricular point stick-ing combined with foot bath can effectively promote the postoperative recovery of patients with adenomyopathy,reduce postoperative pain,improve clinical symptoms and anxiety,which may be related to the analgesic and anti-anxiety effects by regulating neurotransmit-ters and reducing the level of inflammatory factors,with good safety and not easy to relapse.