Objective:To analyze the application of magnetic resonance imaging(MRI)diffusion weighted imaging(DWI)and dynamic contrast enhanced MRI(DCE-MRI)in the diagnosis of prostate cancer(PCA).Methods:105 patients with suspected PCA were selected as the research subjects,and they underwent DWI and DCE-MRI scanning.With pathological biopsy as the gold standard,Kappa consistency test was used to analyze the accuracy,sensitivity and specificity of DWI,DCE-MRI alone and their combined exami-nation in the diagnosis of PCA.Results:66 cases of PCA and 39 cases of benign prostatic lesions were detected by DWI respectively.The Kappa value of DWI and pathological biopsy in diagnosing PCA was 0.918.DCE-MRI detected 60 cases of PCA and 45 cases of benign prostatic lesions,and the Kappa value of PCA diagnosed by DCE-MRI and pathological biopsy was 0.761.The sensitivity and ac-curacy of DWI for PCA diagnosis were 95.59％and 96.19％,which were higher than 85.29％and 88.57％of DCE-MRI(x2=4.168,4.330,P=0.041,0.037).The Kappa value of DWI+DCE-MRI and pathological biopsy for PCA diagnosis was 0.937,and the sensitivity and accuracy were 98.53％and 97.14％,respectively.Conclusion:DWI has higher accuracy and sensitivity in the diagnosis of PCA than DCE-MRI,and the combined diagnosis of the two can up-regulate the diagnostic efficiency of prostate cancer to a certain extent.