< positive > 1 case report case 1: the patient, male, 34 years old, was found to have obvious splenomegaly due to abdominal distension, which was not suitable for out of hospital examination. The spleen was 8.2 cm below the rib, and B-ultrasound showed that the length of the spleen was 21.3 cm. After improving the conventional search for the cause of splenomegaly, the cause of splenomegaly could not be determined, and the patient had no other organ or system damage, so splenectomy was performed. Butterfly shaped erythema appeared on the face of the patient 10 days after surgery, so the examination of systemic lupus erythematosus (SLE) related immune indicators was improved.