Objective:To investigate the correlation between serum uric acid(UA)/albumin(Alb)ratio(sUAR)and sepsis complicated with acute kidney injury(AKI),and to evaluate its predictive value.Methods:The clinical data of 196 patients with sepsis were retrospectively analyzed.According to the occurrence of AKI,they were divided into AKI group(n=95)and non-AKI group(n=101).The differences of serum sUAR level and other clinical indicators between the two groups were compared.Logistic regression anal-ysis was used to screen the risk factors of sepsis-associated AKI(SA-AKI),and the predictive value of related indicators was evaluated by receiver operating characteristic(ROC)curve.Results:Compared with the non-AKI group,the AKI group was older(P＜0.05),the proportion of combined coronary heart disease,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score,sepsis-related organ failure(SOFA)score,procalcitonin(PCT),serum creatinine,UA level,sUAR level were higher(P＜0.05),and the Alb level was lower(P＜0.05).Logistic regression analysis showed that older age(OR=1.718),combined coronary heart disease(OR=1.478),higher SOFA score(OR=2.201)and higher sUAR level(OR=2.487)were risk factors for SA-AKI(P＜0.05).ROC curve analysis showed that the AUC of sUAR in predicting SA-AKI was 0.778,the cutoff value was＞8.2 μmol/g,the sensitivity was 81.1％,and the specificity was 64.4％.The AUC of sUAR combined with SOFA score in predicting SA-AKI was higher,which was 0.855.Conclusion:The increase of serum sUAR level is closely related to SA-AKI.sUAR has a certain predictive value for AKI in pa-tients with sepsis,and combined with SOFA score can improve the predictive efficacy.