Objective:To explore the application effect of first aid process based on medical failure mode and effect analysis(HFMEA)method in the treatment of pernicious placenta previa(PPP).Methods:80 PPP patients were selected and divided into the control group(n=40)and the observation group(n=40)according to the different emergency procedures.The control group was giv-en PPP treatment routine process,and the observation group was given emergency process based on HFMEA method.The time of each link of maternal admission treatment process,occurrence of complications and neonatal outcomes[1 min Apgar score,neonatal intensive care unit(NICU)transfer]were compared between the two groups.Results:The time from admission to green channel start-up,the time from admission to B-ultrasound report,the time from admission to laboratory examination results,and the time from admission to operat-ing room in the observation group were shorter than those in the control group(P＜0.05).The amount of bleeding,red blood cells and platelets in the observation group were less than those in the control group(P＜0.05),and the hospitalization time was shorter than that in the control group(P＜0.05).The total complication rate of pregnant women in the observation group was lower than that of the control group(P＜0.05).The 1 min Apgar score of newborns in the observation group was higher than that in the control group(P＜0.05),and the proportion of 1 min Apgar score≤7 points was less than that in the control group(P＜0.05),the NICU transfer rate between the two groups showed no significant difference(P＞0.05).Conclusion:The implementation of the first aid process based on HFMEA method for PPP patients can optimize the process,shorten the time of each link,improve the efficiency of patient treatment,and improve maternal and infant outcomes.