Objective:To explore the application of quality management combined with preventive nursing model in postoperative infection control of puerperae receiving cesarean section.Methods:155 postpartum women were selected as the research subjects,77 puerperae with cesarean section before the quality management combined with preventive nursing model were listed as control group and were given routine nursing model,and 78 puerperae after the implementation were included in observation group and received quality management combined with preventive nursing model.The intervention time for both groups was 48 hours.The infection status during in-tervention(including incision,lung,and urinary tract infections),colony-related indicators(incision gram-negative bacteria,gram-posi-tive bacteria,fungi,etc.),postoperative recovery status(first exhaust time,first ambulation time,and postoperative hospital stay)and nursing quality(nursing satisfaction scale score)as well as pain degree[Numeric Rating Scale(NRS)score]and postpartum fatigue[Postpartum Fatigue Scale(PFS)score]before intervention and at 48 hours after intervention were compared between the two groups.Results:During the intervention period,the total infection rate,postoperative recovery time and incidence of nursing risk events in ob-servation group were lower than those in control group(P＜0.05).The nursing satisfaction in observation group was higher than that in control group(P＜0.05).There was no statistically significant difference in colony-related indicators between the two groups(P＞0.05).At 48 hours after intervention,the NRS score and PFS scores were reduced in both groups than those before intervention,and the scores were lower in observation group(P＜0.05).Conclusion:Quality management combined with preventive nursing model can effectively control the postoperative infection,promote the recovery,reduce the pain degree and postpartum fatigue,and improve the nursing quality in puerperae with cesarean section.