Objective:To explore the effect of nursing intervention model based on empowerment theory on self-care ability,com-plications and quality of life of rectal cancer patients with stoma.Methods:105 patients who underwent rectal cancer ostomy were in-cluded in the study.According to the different nursing methods,they were divided into control group(n=53)and observation group(n=52).The control group was given routine nursing intervention mode,and the observation group was given nursing intervention mode based on authorization theory.The two groups were intervened for 3 months.The levels of knowledge,belief and practice[the knowl-edge,belief and practice scale for enterostomy patients(CPCKAPS)],self-care ability[the self-care ability assessment scale for enter-ostomy],complications,skin conditions around the stoma[the skin assessment tool around the stoma(DET)]and quality of life[the quality of life scale for enterostomy patients(COH-QOL-OQ)]were compared between the two groups.Results:After intervention,the total score of CPCKAPS and the scores of each dimension in the two groups increased(P＜0.05),and the observation group was higher(P＜0.05).The total score and each dimension score of the self-care ability assessment scale of the two groups increased(P＜0.05),and the observation group was higher(P＜0.05).Compared with 18.86％in the control group,the total incidence of complications in the observation group(5.76％)was lower(P＜0.05).The observation group's total score of DET and the scores of each dimension were lower(P＜0.05).After intervention,the score of COH-QOL-OQ in the two groups increased(P＜0.05),and those in the obser-vation group were higher(P＜0.05).Conclusion:The nursing intervention model based on empowerment theory can improve the knowledge-attitude-practice level and self-care ability of patients with rectal cancer stoma,reduce the incidence of complications,protect the skin around the stoma,and improve the quality of life of patients.