Objective:To analyze the predictive value of non-invasive left ventricular pressure-strain loop(LV-PSL)technology at different times on the prognosis of patients with multivessel coronary heart disease.Methods:All 108 patients with multi-vessel coro-nary artery disease were treated with coronary artery bypass grafting,and LV-PSL was examined before and 1 week after surgery.After 3 months of postoperative follow-up,the patients were divided into good prognosis group(n=74)and poor prognosis group(n=34)according to the incidence of postoperative major adverse cardiovascular events(MACE).The two groups were compared on general in-formation,left-ventricular global longitudinal strain(GLS)and myocardial work parameters.Logistic regression analysis was used for correlation analysis.The predictive efficacy of LV-PSL parameters was analyzed using the receiver operating characteristic(ROC)curve.Results:The levels of GLS and global waste work(GWW)in patients with multi-vessel coronary heart disease 1 week after sur-gery were lower than those before operation,and the overall work index(GWI),overall useful work(GCW)and overall work efficiency(GWE)were higher than those before surgery(P<0.05).Postoperative GWI,GCW and GWE in the poor prognosis group were lower than those in the good prognosis group,while GWW was higher than that in the good prognosis group(P<0.05).Logistic regression a-nalysis showed that GWI,GWE,and GWW were factors influencing the prognosis in patients with coronary heart disease and multivessel disease(P<0.05).The ROC curve showed that the areas under the curve(AUCs)of GWI,GWW and GWE were 0.628,0.695 and 0.827,showed that the AUC of GWE was the largest.Its sensitivity and specificity were 73.53%and 78.38%(P<0.05).Conclu-sion:The LV-PSL technique can be used for prognosis evaluation of patients with coronary heart disease and multivessel disease.GWI,GWW,and GWE at a week after surgery demonstrate relatively high predictive efficacy for the prognosis.