Objective:To explore the predictive value of ultrasound three-dimensional speckle tracking imaging(3D-STI)pa-rameters combined with serum N-terminal pro brain natriuretic peptide(NT proBNP)levels for adverse cardiovascular events(MACE)in patients with acute myocardial infarction after percutaneous coronary intervention(PCI).Methods:82 patients with acute myocardial infarction(AMI)were divided into MACE group(n=18)and non MACE group(n=64)based on the occurrence of MACE during the 6-month follow-up.Collected clinical data of all patients,postoperative ultrasound 3D-STI parameters,and serum NT proBNP levels,compared the differences between the two groups of the above parameters,used Logistic regression analysis to identify independent risk factors for MACE,and drawed receiver operating characteristic(ROC)curves to verify the predictive value of each indicator individual-ly and in combination for MACE.Results:18 out of 82 patients developed MACE(21.95%).The LDL,cTnT,and serum NT proBNP levels in the MACE group were higher than those in the non MACE group(P＜0.05),while LVEF,GLS,GCS,GRS,GAS,rotation an-gle,and rotation angle were lower than those in the non MACE group(P＜0.05).Logistic regression analysis showed that GLS(OR=3.102),GCS(OR=2.989),GRS(OR=3.053),and serum NT proBNP(OR=2.956)were independent risk factors for MACE after PCI in AMI patients(P＜0.05).The ROC curve showed that when all indicators were used in combination,the AUC was 0.976,and the sensitivity and specificity were 94.44%and 95.31%,respectively.Conclusion:Ultrasound 3D-STI related parameters GLS,GCS,GRS combined with serum NT proBNP levels can further improve the predictive value of MACE occurrence in AMI patients after PCI.