Objective:To explore the effect of combined application of labor analgesia and phloroglucinol on parturients with cer-vical immaturity and the influence on neonatal umbilical artery blood gas indexes.Methods:226 parturients with cervical immaturity were classified into control group(routine treatment,n=105)and observation group(routine treatment+labor analgesia+phloro-glucinol,n=121)by means of different prenatal treatment methods.The cervical maturity promoting effect,labor process and pain sta-tus at different time points in the two groups were evaluated.The changes of umbilical artery blood gas indexes were observed in both groups,and the pregnancy outcomes were compared.Results:The observation group had higher total effective rate of cervical maturity promoting than the control group,and the first stage of labor incubation period,active period and total labor in the observation group were shorter than those in the control group(P<0.05).The visual analogue scale(VAS)scores at various time points were lower in the observation group(P<0.05).The pH value,partial pressure of carbon dioxide and partial pressure of oxygen in the observation group were better than those in the control group(P<0.05).The adverse pregnancy outcomes incidence in observation group was low-er compared to the control group(P<0.05).Conclusion:The combined application of labor analgesia and phloroglucinol can promote the cervical maturity of primiparas,shorten the labor process,relieve the pain,improve the umbilical artery blood gas indexes of neo-nates,and reduce the rate of adverse pregnancy.