Objective:To analyze the application effect of percutaneous electrical acupoint stimulation combined with modified Qusuoshengji Powder in patients after perianal abscess surgery.Methods:A total of 120 patients with perianal abscess were selected and divided into two groups according to the treatment plan:the control group(percutaneous electrical acupoint stimulation)and the study group(percutaneous electrical acupoint stimulation+modified Qusu Shengji Powder),with 60 cases in each group and the treatment course was 14 days.The therapeutic effects,wound healing conditions,TCM syndrome scores,inflammatory factors,cellular immune balance and safety of the two groups were compared.Results:The total effective rate of the study group was higher than that of the con-trol group(P<0.05).The granulation tissue score of the study group was lower than that of the control group(P<0.05),the ap-pearance time of wound epithelium and the shedding time of necrotic flesh were both shorter than those of the control group(P<0.05),and the wound healing rate was higher than that of the control group(P<0.05).After treatment,the scores of TCM syndrome indicators and interferon-γ(IFN-γ)in both groups decreased(P<0.05),and the study group was lower than the control group(P<0.05).After treatment,interleukin 4(IL-4)and the ratio of IL-4/IFN-γ increased in both groups(P<0.05),and the study group was higher than the control group(P<0.05).There was no statistically significant difference in safety between the two groups(P>0.05).Conclusion:Percutaneous electrical acupoint stimulation combined with modified Qusuoshengji Powder for the treatment of pa-tients after perianal abscess surgery can promote wound healing,inhibit inflammatory responses and regulate immune balance.The ther-apeutic effect is remarkable and the safety is good.